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block14_35.jpg - Fig. 18, 93W5540, Ovary, Corpus Luteum, H&EThe granulosa lutein cells (GLC) contain a large spherical nucleus and a  large amount of cytoplasm. Theca lutein cells (TLC) also contain a  spherical nucleus, but the cells are smaller than the granulosa lutein cells.  Thus, when identifying the two cell types, aside from location, note that  the nuclei of adjacent theca lutein cells generally appear to be closer to  each other than nuclei of adjacent granulosa lutein cells. The connective  tissue (CT) and small blood vessels that invaded the mass of corpus  luteum can be identified as the flattened and elongated components.If pregnancy occurs, the corpus luteum remains functional; if pregnancy  does not occur, the corpus luteum regresses after having reached a point  of peak development, roughly 2 weeks after ovulation. The regressing  cellular components of the corpus luteum are replaced by fibrous  connective tissue, and the structure is then called a corpus albicans.

Fig. 18, 93W5540, Ovary, Corpus Luteum, H&E The granulosa lutein cells (GLC) contain a large spherical nucleus and a large amount of cytoplasm. Theca lutein cells (TLC) also contain a spherical nucleus, but the cells are smaller than the granulosa lutein cells. Thus, when identifying the two cell types, aside from location, note that the nuclei of adjacent theca lutein cells generally appear to be closer to each other than nuclei of adjacent granulosa lutein cells. The connective tissue (CT) and small blood vessels that invaded the mass of corpus luteum can be identified as the flattened and elongated components.
If pregnancy occurs, the corpus luteum remains functional; if pregnancy does not occur, the corpus luteum regresses after having reached a point of peak development, roughly 2 weeks after ovulation. The regressing cellular components of the corpus luteum are replaced by fibrous connective tissue, and the structure is then called a corpus albicans.
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