Block14/Fig. 15, 93W7260, Ovary Mature, Human, H&E

block14_29.jpg - Fig. 15, 93W7260, Ovary Mature, Human, H&EThe more advanced follicle is a secondary follicle (SF). The oocyte in this follicle is surrounded by several layers of follicular cells that, at this stage, are identified as granulosa cells (G). At a slightly earlier time, small lakes of fluid formed between the follicular cells, and these lakes have now fused into a well-defined larger cavity called the follicular antrum (A). The antrum is also filled with fluid. The substance has been retained as an eosinophilic precipitate in the antrum of the secondary follicles shown here. In secondary follicles, particularly in the larger follicle with the antrum, the surrounding stromal cells have become altered to form two distinctive layers designated theca intema (TI) and theca extema (TE). The theca interna is a more cellular layer, and the cells are epithelioid. In contrast, the theca extema is a connective tissue layer. Its cells are more spindle shaped.

Fig. 15, 93W7260, Ovary Mature, Human, H&E The more advanced follicle is a secondary follicle (SF). The oocyte in this follicle is surrounded by several layers of follicular cells that, at this stage, are identified as granulosa cells (G). At a slightly earlier time, small lakes of fluid formed between the follicular cells, and these lakes have now fused into a well-defined larger cavity called the follicular antrum (A). The antrum is also filled with fluid. The substance has been retained as an eosinophilic precipitate in the antrum of the secondary follicles shown here. In secondary follicles, particularly in the larger follicle with the antrum, the surrounding stromal cells have become altered to form two distinctive layers designated theca intema (TI) and theca extema (TE). The theca interna is a more cellular layer, and the cells are epithelioid. In contrast, the theca extema is a connective tissue layer. Its cells are more spindle shaped.

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