Block10-2/Fig 9. 93W4600, Pancreas (sec.) H&E.

block10-2_21.jpg - Fig 9. 93W4600, Pancreas (sec.) H&E.Pancreatic acini (PA) are made up of irregular clusters ofpyramid-shaped secretory cells. The apices of secretory cellssurround a minute central lumen (the intercalated duct, I)which represents the terminal end of the duct system. Theintercalated ducts are lined by simple low cuboidal epitheliumand drain into small intralobular ducts (IaD). The centres of theacini frequently contain one or more nuclei of centroacinarcells (C) with pale nuclei and sparse pale-stained cytoplasm;these represent the terminal lining cells of intercalated ductsactually. The acinar cells are typical protein-secreting cells.The nuclei are basally located and surrounded by basophiliccytoplasm crammed with rough endoplasmic reticulum; theapices of the cells are packed with eosinophilic zymogensecretory granules.

Fig 9. 93W4600, Pancreas (sec.) H&E. Pancreatic acini (PA) are made up of irregular clusters of pyramid-shaped secretory cells. The apices of secretory cells surround a minute central lumen (the intercalated duct, I) which represents the terminal end of the duct system. The intercalated ducts are lined by simple low cuboidal epithelium and drain into small intralobular ducts (IaD). The centres of the acini frequently contain one or more nuclei of centroacinar cells (C) with pale nuclei and sparse pale-stained cytoplasm; these represent the terminal lining cells of intercalated ducts actually. The acinar cells are typical protein-secreting cells. The nuclei are basally located and surrounded by basophilic cytoplasm crammed with rough endoplasmic reticulum; the apices of the cells are packed with eosinophilic zymogen secretory granules.

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